Sorbact dressings for postoperative wounds
Surgical site infections (SSIs) are a huge health problem worldwide. SSI is a common postoperative complication in vascular, obstetric, gynecologic, gastric, thoracic, and cardiovascular surgery. It prolongs hospitalization and contributes to significant morbidity and mortality.[1]View reference information [2]View reference information
Don't forget the last step
Several actions are being taken to prevent surgical site infections, both preoperative, during and after the operation, e.g. pre-op disinfectants, two pairs of gloves and effective ventilation. However, one important factor that is often missed in the overall strategy is to reduce microbes at the incision site and the preventive and treatment role of using a suitable dressing. This is stated in the recent international guidelines (scroll down).
Sorbact is recommended by NICE[3]View reference information
NICE medical technologies guidance mtg55 suggests that Leukomed Sorbact:
- Reduces SSI in caesarean section and vascular surgery
- May reduce antibiotic use
- May reduce readmissions from wound complications
- Could save the NHS up to £5.3 million per year for caesarean section and up to £1.2 million per year for vascular surgery
- Cost savings are expected
Leukomed is a registered trademark of BSN Medical GmbH
Sorbact for preventing and managing SSI across health care sectors
In these international guidelines Sorbact is recommended across health care sectors.[4]View reference information It can be used for infection prevention as well as for treating infected surgical wounds.
See table 9 – Wound dressings for the management of surgical wounds (page 33).
Sorbact reduces the risk of infection in wounds
Sorbact bacteria and fungi binding dressings prevent and treat wound infections by lowering the bioburden.[5]View reference information [6]View reference information Bacteria irreversibly bind and anchor to the unique Sorbact surface. Safe and effective removal of bacteria reduces the bioburden in wounds which facilitates the healing process. With the Sorbact mode of action, development of bacterial or fungal resistance is not expected.
Since there are no active agents released into the wound[7]View reference information, Sorbact dressings can be used right from the start, in all patients, in the short-term or for prolonged treatment of already infected wounds.
Calculate the potential value of preventing SSI
SSI has become a huge public health problem because it contributes to significant morbidity, mortality and financial consequences. An SSI is estimated to add approximately 3–21 days to a patient’s hospital stay. This results in additional treatment costing between 900€–7300€[8]View reference information, depending on the type of surgery and severity of the infection.[9]View reference information [10]View reference information
Estimate the cost of SSIs
Number of procedures per period
Current incidence of SSI
Potential incidence of SSI
Average cost of an SSI
The cost of dressings (to protect and prevent infection) is not included in the calculation. It is often a minor part of the total.
total number of SSIs
total cost
Add no of procedures per period
A period is often a year for hospital, region or country.
Current incidence of SSI
The incidence rate (the % of new SSIs within a time period) following a caesarean section vary between 3%-15%[1], it’s 10-15% following vascular surgery, rising to 30% in trials specifically monitoring SSI as an outcome.[2] [3]
- Saeed KBM, Greene RA, et al. 2017. Incidence of surgical site infection following caesarean section: a systematic review and meta-analysis protocol. BMJ Open. 7:e013037. External link to reference1 (Opens in new tab)
- Matatov T, Reddy KN, et al. 2013. Experience with a new negative pressure incision management system in prevention of groin wound infection in vascular surgery patients. J Vasc Surg. 57(3):791-795. External link to reference2 (Opens in new tab)
- Turtiainen J, Saimanen EIT, et al. 2012. Effect of triclosan-coated sutures on the incidence of surgical wound infection after lower limb revascularization surgery: a randomized controlled trial. World J Surg. 36(10):2528-2534. External link to reference3 (Opens in new tab)
Potential incidence of SSI
The potential incidence is the expected incidence after a change has been introduced that affects the current incidence.
Average cost of an SSI
Average cost for treating an SSI is approximately 4400€ at 2017 prices.[1] [2] The main cost driver is extra length of stay in hospital. Approximate additional costs attributable to SSI vary between 900€-7300€ depending on the type of surgery and the severity of the infection.[3]
Total cost of SSIs = number of SSIs x average cost of an SSI
- Jenks PJ, Laurent M, et al. 2014. Clinical and economic burden of surgical site infection (SSI) and predicted financial consequences of elimination of SSI from an English hospital. J Hosp Infect. 86(1):24-33. External link to reference1 (Opens in new tab)
- Stanirowski PJ, Davies H, et al. 2019. Cost-effectiveness of a bacterial-binding dressing to prevent surgical site infection following caesarean section. J Wound Care. 28(4):222-228. External link to reference2 (Opens in new tab)
- Leaper DJ, Van Goor H, et al. 2004. Surgical site infection – a European perspective of incidence and economic burden. Int Wound J. 1(4):247-273. External link to reference3 (Opens in new tab)
Evidence on Sorbact in postoperative wounds
Proven to prevent and treat wound infection in more than 40 clinical studies and in publications including over 7,000 patients, Sorbact has more than 30 years of successful use in clinical practice. Today Sorbact is helping patients in over 65 countries around the world and we are continuing this important work by collecting clinical data.
Sorbact reduces the incidence of SSI in vascular surgery
A comparative study to assess the impact of Sorbact on the incidence of SSI in vascular surgery. 200 patients undergoing vascular surgery. Rate of SSI day 5-7:10% (Control) vs 1% (Sorbact) p=<0.01. Rate of SSI day 30: 19% (Control) vs 10% (Sorbact) p=0.11.
Bua N, Smith GE, et al. 2017. Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery. Ann Vasc Surg. 44:387-392. https://doi.org/10.1016/j.avsg.2017.03.198 (Opens in new tab)
Sorbact prevents wound infections
A randomized controlled study among 543 patients undergoing elective or emergency caesarean section, comparing Sorbact Surgical Dressing to standard surgical dressing (1.8 % vs. 5.2 %) p=0.04.
Stanirowski PJ, Bizoń M, et al. 2016. Randomized Controlled Trial Evaluating Dialkylcarbamoyl Chloride Impregnated Dressings for the Prevention of Surgical Site Infections in Adult Women Undergoing Cesarean Section. Surg Infect (Larchmt). 17(4):427-435. doi.org/10.1089/sur.2015.223 (Opens in new tab)
References
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WHO. 2011. Report on the burden of endemic health care-associated infection worldwide. Geneva: World Health Organization.
External link to reference1 (Opens in new tab) Back -
European Centre for Disease Prevention and Control. 2013. Point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals. Stockholm: ECDC.
External link to reference2 (Opens in new tab) Back -
NICE. 2021. Leukomed Sorbact for preventing surgical site infection. NICE National Institute for Health and Care Excellence. 1-17.
External link to reference3 (Opens in new tab) Back -
Stryja J, Sandy-Hodgetts K, et al. 2020. Surgical site infection: preventing and managing surgical site infection across health care sectors. J Wound Care. 29(Sup2b):1-72.
External link to reference4 (Opens in new tab) Back -
Gentili V, Gianesini S, et al. 2012. Panbacterial real-time PCR to evaluate bacterial burden in chronic wounds treated with Cutimed Sorbact. Eur J Clin Microbiol Infect Dis. 31(7):1523-1529.
External link to reference5 (Opens in new tab) Back -
Mosti G, Magliaro A, et al. 2015. Comparative study of two antimicrobial dressings in infected leg ulcers: a pilot study. J Wound Care. 24(3):121-122, 124-127.
External link to reference6 (Opens in new tab) Back -
Data on file. Abigo Medical.
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Leaper DJ, Van Goor H, et al. 2004. Surgical site infection – a European perspective of incidence and economic burden. Int Wound J. 1(4):247-273.
External link to reference8 (Opens in new tab) Back -
European Centre for Disease Prevention and Control. 2013. Point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals. Stockholm: ECDC.
External link to reference9 (Opens in new tab) Back -
Leaper DJ, Van Goor H, et al. 2004. Surgical site infection – a European perspective of incidence and economic burden. Int Wound J. 1(4):247-273.
External link to reference10 (Opens in new tab) Back